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Effects of perioperative statin use on cardiovascular complications in patients submitted to non-cardiac surgery: protocol for a systematic review, meta-analysis, and trial sequential analysis

  • Erica Aranha Suzumura1Email author,
  • Rodrigo Antonini Ribeiro2, 3, 4,
  • Leticia Kawano-Dourado1, 5,
  • Pedro Gabriel de Barros e Silva1, 7,
  • Claudia Oliveira1,
  • Mabel Fernandes Figueiró1,
  • Alexandre Biasi Cavalcanti1,
  • Renato D. Lopes1, 6, 7 and
  • Otavio Berwanger1
Systematic Reviews20176:116

Received: 25 July 2016

Accepted: 16 May 2017

Published: 19 June 2017

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
25 Jul 2016 Submitted Original manuscript
6 Sep 2016 Author responded Author comments - Erica Aranha Suzumura
Resubmission - Version 2
6 Sep 2016 Submitted Manuscript version 2
24 Feb 2017 Reviewed Reviewer Report - Andrea Lemos
5 Mar 2017 Reviewed Reviewer Report - Paulo Jannuzzi Cunha
9 May 2017 Author responded Author comments - Erica Aranha Suzumura
Resubmission - Version 3
9 May 2017 Submitted Manuscript version 3
16 May 2017 Editorially accepted
19 Jun 2017 Article published 10.1186/s13643-017-0500-0

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Research Institute, Hospital do Coração (HCor), São Paulo, Brazil
Graduate Program in Epidemiology, Federal University of Rio Grande do Sul, Porto Alegre, Brazil
National Institute of Science and Technology for Health Technology Assessment, CNPq, Brazil
School of Medicine, Faculdade Meridional – IMED, Passo Fundo, Brazil
Pulmonary Division – Heart Institute (InCor) University of Sao Paulo Medical School, São Paulo, Brazil
Duke Clinical Research Institute (DCRI), Durham, USA
Brazilian Clinical Research Institute (BCRI), São Paulo, Brazil