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Table 5 Subgroup analysis of between-session MEP amplitude reliability

From: The number of stimuli required to reliably assess corticomotor excitability and primary motor cortical representations using transcranial magnetic stimulation (TMS): a systematic review and meta-analysis

 

Pooled ICC (95% CI)

Subgroup

N

3 stimuli

4 stimuli

5 stimuli

10 stimuli

15 stimuli

Healthy only

5

NA

0.65 (0.15 to 0.88)

0.79 (0.62 to 0.89)

0.89 (0.76 to 0.95)

0.91 (0.70 to 0.98)

CVA only

1

NA

0.28 (−0.29 to 0.71)

NA

0.30 (−0.33 to 0.75)

NA

Age <65 years

5

NA

0.48 (0.04 to 0.76)

0.82 (0.64 to 0.91)

0.83 (0.56 to 0.94)

0.91 (0.70 to 0.98)

Age >65 years

1

NA

NA

0.65 (0.03 to 0.91)

NA

NA

Upper limb onlya

3

NA

NA

0.82 (0.64 to 0.91)

0.94 (0.76 to 0.99)

0.95 (0.89 to 0.98)

Lower limb onlyb

2

NA

0.48 (0.04 to 0.76)

NA

0.63 (−0.10 to 0.92)

NA

Submental group only

1

NA

NA

0.66 (0.05 to 0.91)

0.72 (0.16 to 0.95)

0.69 (0.11 to 0.92)

<72 h between sessions

4

NA

NA

0.79 (0.62 to 0.89)

0.90 (0.74 to 0.97)

0.91 (0.70 to 0.98)

>72 h between sessions

2

NA

0.48 (0.04 to 0.76)

NA

0.63 (−0.10 to 0.92)

NA

  1. ICC intraclass correlation coefficient, CI confidence interval, N number of participant cohorts, CVA participants with 6 months post-cerebrovascular accident, NA not available
  2. aAlso, analysis of resting conditions only
  3. bAlso, analysis of active conditions only