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Table 4 Subgroup analysis of within-session MEP amplitude reliability

From: The number of stimuli required to reliably assess corticomotor excitability and primary motor cortical representations using transcranial magnetic stimulation (TMS): a systematic review and meta-analysis

  Pooled ICC (95% CI)
Subgroup N 3 stimuli 4 stimuli 5 stimuli 10 stimuli 15 stimuli
Healthy only 5 0.69 (0.47 to 0.83) 0.73 (0.55 to 0.85) 0.92 (0.87 to 0.95) 0.96 (0.90 to 0.98) 0.98 (0.95 to 0.99)
CVA only 1 NA 0.76 (0.38 to 0.92) NA 0.81 (0.41 to 0.95) NA
Age <65 years 5 0.80 (0.34 to 0.95) 0.80 (0.61 to 0.90) 0.90 (0.79 to 0.95) 0.94 (0.84 to 0.98) 0.98 (0.95 to 0.99)
Age >65 years 1 0.65 (0.38 to 0.82) 0.66 (0.39 to 0.82) 0.94 (0.88 to 0.97) NA NA
Upper limb onlya 3 0.65 (0.38 to 0.82) 0.66 (0.39 to 0.82) 0.92 (0.86 to 0.96) 0.98 (0.94 to 0.99) 0.98 (0.95 to 0.99)
Lower limb onlyb 2 NA 0.75 (0.49 to 0.89) NA 0.86 (0.68 to 0.95) NA
Submental group only 1 0.80 (0.34 to 0.95) 0.89 (0.59 to 0.97) 0.92 (0.67 to 0.98) NA NA
  1. ICC intraclass correlation coefficient, CI confidence interval, N number of participant cohorts, CVA participants with 6 months post-cerebrovascular accident, NA not available
  2. aAlso, analysis of resting conditions only
  3. bAlso, analysis of active conditions only