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Table 4 Subgroup analysis of within-session MEP amplitude reliability

From: The number of stimuli required to reliably assess corticomotor excitability and primary motor cortical representations using transcranial magnetic stimulation (TMS): a systematic review and meta-analysis

 

Pooled ICC (95% CI)

Subgroup

N

3 stimuli

4 stimuli

5 stimuli

10 stimuli

15 stimuli

Healthy only

5

0.69 (0.47 to 0.83)

0.73 (0.55 to 0.85)

0.92 (0.87 to 0.95)

0.96 (0.90 to 0.98)

0.98 (0.95 to 0.99)

CVA only

1

NA

0.76 (0.38 to 0.92)

NA

0.81 (0.41 to 0.95)

NA

Age <65 years

5

0.80 (0.34 to 0.95)

0.80 (0.61 to 0.90)

0.90 (0.79 to 0.95)

0.94 (0.84 to 0.98)

0.98 (0.95 to 0.99)

Age >65 years

1

0.65 (0.38 to 0.82)

0.66 (0.39 to 0.82)

0.94 (0.88 to 0.97)

NA

NA

Upper limb onlya

3

0.65 (0.38 to 0.82)

0.66 (0.39 to 0.82)

0.92 (0.86 to 0.96)

0.98 (0.94 to 0.99)

0.98 (0.95 to 0.99)

Lower limb onlyb

2

NA

0.75 (0.49 to 0.89)

NA

0.86 (0.68 to 0.95)

NA

Submental group only

1

0.80 (0.34 to 0.95)

0.89 (0.59 to 0.97)

0.92 (0.67 to 0.98)

NA

NA

  1. ICC intraclass correlation coefficient, CI confidence interval, N number of participant cohorts, CVA participants with 6 months post-cerebrovascular accident, NA not available
  2. aAlso, analysis of resting conditions only
  3. bAlso, analysis of active conditions only