|
Author
|
Partial Foot Amputation
|
Transtibial Amputation
|
A
|
B
|
C
|
D
|
E
|
F
|
G
|
H
|
I
|
J
|
K
|
L
|
M
|
N
|
O
|
P
|
Q
|
R
|
S
|
T
|
U
|
V
|
W
|
|---|
| |
(n)
|
DM (%)
|
Male (%)
|
Age M(SD)
|
(n)
|
DM (%)
|
Male (%)
|
Age, M(SD)
|
|---|
|
Andrews et al. [77]
|
307
|
79
|
70
|
65.5(14.8)
| | | | | | |
X
| | |
X
| | |
X
| | | |
X
|
X
| | | | | | | | | |
|
Boutoille et al. [382]
|
19
|
100
| |
68 (median)^
|
6
|
100
| |
68 (median)^
| | | | | |
X
| |
X
|
X
| | | | | | | | | | | | | |
X
|
|
Brown et al. [173]
|
64^
|
100
| |
57˭
|
18
|
100
| |
59(12)
| | | | | |
X
| |
X
| | | |
X
| | | | | | |
X
|
X
| | | |
|
Czerniecki et al. [76]
|
27
|
86
|
≈96^˭
|
≈64^˭
|
39
|
86
|
≈96^
|
≈64^
|
X
|
X
|
X
|
X
| | | |
X
|
X
| |
X
|
X
|
X
| | |
X
|
X
|
X
|
X
|
X
| | |
X
|
|
Czerniecki et al. [34]
|
27
|
100
| |
63(8)
|
52
|
85
| |
62(9)
|
X
|
X
|
X
|
X
| | | |
X
|
X
| |
X
|
X
|
X
| | |
X
|
X
|
X
|
X
|
X
| | |
X
|
|
Dillingham and Pezzin [66]
|
379
|
70^
|
49^
|
75^
|
949
|
70^
|
49^
|
75^
|
X
|
X
| | | | | | | | | |
X
| | | | | | | | | |
X
| |
|
Dillingham et al. [28]
|
1451
|
83
|
52^
|
74^
|
950
|
79
|
52^
|
74^
|
X
| | | | | | | | | | |
X
| | | | | | | | | |
X
| |
|
Evans et al. [18]
|
88
|
100
|
57
|
70
|
25
|
100
|
76
|
69
| | | | | | | | |
X
|
X
| | |
X
| |
X
| |
X
| |
X
| |
X
| |
X
|
|
Glaser et al. [65]
|
1140
|
74
|
67
|
67(14)
| | | | |
X
| | | | | | | |
X
| | | |
X
| | | | | |
X
| | | | |
|
Griffin et al. [59]
|
63
|
68
|
87
|
69
| | | | |
X
| |
X
| | | | | |
X
| | | |
X
| |
X
|
X
| |
X
|
X
| | |
X
| |
|
Hambleton et al. [63]
|
123
|
100
|
45^
|
67(13)
|
47
|
100
|
45э
|
76(10)ø
|
X
| | |
X
| | |
X
|
X
|
X
|
X
| | |
X
|
X
| | |
X
| | | | | |
X
|
|
Izumi et al. [27, 67]
|
213
|
100
|
70˭
|
52˭
| | | | |
X
| |
X
| | | | | | | | | | | |
X
|
X
|
X
|
X
|
X
| | | | |
|
Jindeel and Narahara [68]
|
594
|
93
|
75^
|
≈55α
| | | | |
X
| | | | | | | |
X
| | | | | | | | | | | | | | |
|
Jones and Marshall [69]
|
29
|
100
|
100
|
71 (7)
|
30
|
100
|
100
|
71(7)
| | | | | |
X
|
X
| | |
X
| | |
X
| |
X
|
X
|
X
| |
X
| | | | |
|
Kono and Muder [70]
|
116
|
80
|
99
|
67(11)
| | | | | | |
X
|
X
|
X
| | | |
X
|
X
| | | |
X
|
X
| | |
X
|
X
| |
X
|
X
|
X
|
|
Kristensen et al. [61]
|
15
|
53
|
80
|
74(15)
|
31
|
39
|
58
|
74(13)
| |
X
| | | | | | | | | |
X
| | | | | | | | |
X
|
X
| |
|
Lakstein et al. [64]
|
35
|
100
|
66
|
66.6(10.2)
| | | | | | | | |
X
| | | | | | | | | | | | | | | | | |
X
|
|
Marzen-Groller et al. [75]
|
13
| | | |
19
| | | | | | | | | | | | | | | | | | | | | | | | | | |
|
Mayfield et al. [71]
|
2234
|
61^
|
99^
|
66^
|
1381
|
61^
|
99^
|
66^
|
X
|
X
| | | | | | |
X
| | | | | | | |
X
| |
X
| | | | |
|
Norvell et al. [33]
|
27
|
100
|
100
|
63(8)
|
52b
|
85
|
88
|
62(9)
|
X
|
X
|
X
|
X
| | | |
X
| | |
X
|
X
|
X
| | |
X
|
X
|
X
|
X
| | | |
X
|
|
Peters et al. [35]
|
26
|
100
|
77^
|
57(10)^
|
8
|
100
|
77^
|
57(10)^
| | | | | |
X
| |
X
|
X
| | | | |
X
|
X
| | | | | | | | |
|
Quigley et al. [36]
|
10
|
80
|
70
|
63(10)
|
23
|
70
|
60
|
68(10)
| | | | | | | | |
X
|
X
| | | | | | | | |
X
| | | |
X
|
|
Sandnes et al. [72]
|
4434
|
66
|
61
|
66(16)
|
5298
|
63
|
61.9
|
68(16)
| | | | | | | | |
X
| | |
X
| | | | |
X
| |
X
| | | |
X
|
|
Sheahan et al. [73]
|
670
|
92
|
70
| | | | | | | |
X
| | | | | |
X
| | | |
X
| |
X
| | | |
X
| | | | |
|
Stone et al. [74]
|
74
|
100
|
87
|
64 (No SD)
| | | | | | |
X
| | | |
X
| | | | | | | | | | | |
X
| |
X
| | |
|
Vamos et al. [60]
|
5487*
|
40^
|
59˭ψ
|
66˭ψ
| | | | | |
X
| | | | | | |
X
| | | | | | | | | | | | | | |
|
Winell et al. [62]
|
706
|
100
| | | | | | | | | | | | | | |
X
| | | | | | | | | | | | | | |
|
Younger et al. [58]
|
21
|
100
|
81
|
60.4(11.8)
|
21
|
100
|
81
|
56.3(10.9)
| | |
X
| |
X
|
X
| | |
X
| | | | | | | | | |
X
| | | | |
- A: Race/Ethnicity; B: Socio-demographic details; C: Smoking/Tobacco Use; D: Other Lifestyle Behaviors; E: Exams/Tests; F: HbA1c; G: Other Biomarkers; H: BMI; I: Diabetes; J: Sensation; K: Mental Health; L: Comorbidities; M: Blood Pressure; N: Other Blood Flow/Pressure Issues; O: CAD; P: Stroke/CVA; Q: Other Cardiovascular Issues; R: Revascularization; S: Renal Issues; T: Mobility; U: Re-amputation; V: Amputation Surgery; W: Other; DM Diabetes Mellitus, M(SD) Mean (Standard Deviation), TMA Transmetatarsal Amputation; Sociodemographic details include education level, relationship status, employment status, residential status, geographic region, economic status, Modified Social Support Score; Other lifestyle behaviors include alcohol use and malnutrition; Exams/Tests include physical exams, lab tests and cultures; Other biomarkers include GHb and hyperlipidemia; Mental health includes major depressive disorders and post-traumatic stress disorder; BMI Body Mass Index; Sensation includes neuropathy, impaired protective sensation, Vibration Perception Threshold; Comorbidities include the Charlson Comorbidity Index, frequency of comorbidities and the Anesthesiology Association of America Physical Status scale; Other blood flow/pressure issues include missing pulses, ankle brachial index, Doppler for ankle blood pressure; CAD Coronary Artery Disease, CVA Cerebrovascular Accident; Other Cardiovascular problems include cardiovascular disease, myocardial infarct, heart attack, peripheral arterial disease, peripheral vascular disease and chronic obstructive pulmonary disease; Renal issues include nephropathy, renal dialysis, chronic renal failure, renal insufficiency and end stage renal disease; Mobility include the Locomotor Capability Index-5 and Volpicelli Ambulatory Scale; Amputation surgery includes urgency of surgery, cause/level of amputation, age at first amputation, operation time, length of stay, number of amputation related admissions in 12 months post-index amputation, wound healing, post-op infection and post-op antibiotic use; Other includes immunosuppressant use, joint replacement, Charcot collapse, footwear type, perceived premorbid health, retinopathy, ulcer and traumatic brain injury. ^based on lower limb sample as a whole. *in year 2005. bwith 10 drop outs over 12 months. αstratified by sex. ψin most recent year reported (2005/6). эbased on case subjects for whole lower limb sample; øbased on ‘major’ group including transtibial/transfemoral amputation. ˭weighted to summarize data presented by discrete cohorts (e.g., different amputation levels)
