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Table 2 Overview of prognostic factors extracted for IDP analyses and the role of the variable in moderator analysis

From: Rational and design of an individual participant data meta-analysis of spinal manipulative therapy for chronic low back pain—a protocol

Individual subject characteristics

Prognostic factors

 
 

Age

Confirmatory

 

Gender

Exploratory

 

Height, weight, body mass index

Exploratory

 

Ethnicity/race

Exploratory

Lifestyle factors

 

Participation in sports activities or physical fitness level

Exploratory

 

Smoking

Exploratory

 

Alcohol use

Exploratory

Sociodemographic characteristics

 

Marital status

Exploratory

 

Level of education

Exploratory

 

Income

Exploratory

 

Employment status

Exploratory

Nature and severity of the low back pain

 

Duration of the low back pain

Confirmatory

 

Non-specific

Exploratory

 

Radiation

Exploratory

 

Previous low back pain treatment received

Exploratory

Comorbidities, e.g., diabetes, heart disease

 

Presence of comorbidities

Exploratory

Number of comorbidities

Exploratory

Category of comorbidities

Exploratory

 Type of treatment

Manipulation, mobilization, combination

 

 Psychosocial factors

e.g., Back Depression Inventory, Fear Avoidance Beliefs Questionnaire

Confirmatory

Treatment preference/ expectation

e.g., preference for treatment, previous experience with treatment, expectation to final improvement, self-efficacy scale/beliefs

Confirmatory