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Table 1 Overview of outcomes extracted for IDP analyses and the role of the variable in moderator analysis

From: Rational and design of an individual participant data meta-analysis of spinal manipulative therapy for chronic low back pain—a protocol

Domain

Assessment instruments/measurements scales

Exploratory/confirmatory moderator analysis

Primary outcomes

Pain

e.g., Visual Analog Scale Numerical Rating Scale, Aberdeen Back Pain Scale

Confirmatory (the baseline measurement of pain)

Physical functioning

e.g., Oswestry Disability Index, Roland Morris Disability Questionnaire

Confirmatory (the baseline measurement of physical functioning)

Secondary outcomes

 Recovery

Global assessment

 

 Return-to-work

e.g., numbers of days of work absenteeism, number of participants that returned to work

 

 Quality of life

Short Form-36 Item Health Survey, EuroQol (EQ5D)

Confirmatory (the baseline measurement of quality of life)

 Satisfaction

Satisfaction with treatment Satisfaction with outcome

 

 Reduction in frequency of analgesic use