|
ID
|
Total classification
|
Sequence generation (selection bias)
|
Allocation concealment (selection bias)
|
Blinding (performance bias)
|
Outcome completeness
|
Selective outcome reporting
|
Other biases
|
|---|
|
1
|
High
|
+
|
?
|
+
|
+
|
-
|
-
|
|
2
|
Unclear
|
+
|
+
|
+
|
?
|
?
|
+
|
|
3
|
High
|
+
|
+
|
-
|
-
|
+
|
?
|
|
4
|
High
|
-
|
-
|
?
|
?
|
+
|
?
|
|
5
|
High
|
-
|
+
|
+
|
-
|
?
|
+
|
|
6
|
High
|
-
|
+
|
-
|
-
|
?
|
-
|
|
7
|
High
|
+
|
+
|
NA
|
-
|
+
|
+
|
|
8
|
High
|
?
|
-
|
-
|
+
|
-
|
?
|
|
9
|
High
|
-
|
-
|
?
|
?
|
-
|
+
|
|
10
|
High
|
-
|
?
|
?
|
+
|
-
|
?
|
|
11
|
High
|
NA
|
NA
|
NA
|
-
|
-
|
+
|
|
12
|
Unclear
|
NA
|
NA
|
NA
|
+
|
?
|
+
|
|
13
|
High
|
NA
|
NA
|
?
|
-
|
-
|
+
|
|
14
|
High
|
-
|
-
|
?
|
-
|
-
|
?
|
|
15
|
Unclear
|
?
|
?
|
+
|
?
|
?
|
+
|
|
16
|
High
|
-
|
-
|
?
|
-
|
-
|
?
|
|
17
|
High
|
NA
|
NA
|
-
|
-
|
+
|
?
|
|
18
|
High
|
-
|
-
|
?
|
?
|
?
|
?
|
- + low risk of bias; ? unclear risk of bias; - high risk of bias; NA not applicable
