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Table 1 Definition of the four levels of evidence by GRADE [15]

From: Chinese herbal medicine for the treatment of primary hypertension: a methodology overview of systematic reviews

Quality level Definition
High We are very confident that the true effect lies close to that of the estimate of the effect
Moderate We are moderately confident in the effect estimate: the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different
Low Our confidence in the effect estimate is limited: the true effect may be substantially different from the estimate of the effect
Very low We have very little confidence in the effect estimate: the true effect is likely to be substantially different from the estimate of effect