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Table 3 Case study B: comparison of PICO (population, intervention, comparator, outcome) criteria between the existing systematic reviews (Galvao et al. [14], Jefferson et al. [15], Fell et al. [13], and McMillan et al. [16]) and our own new review

From: Use of existing systematic reviews for evidence assessments in infectious disease prevention: a comparative case study

  Galvao et al. [14] Jefferson et al. [15] Fell et al. [13] McMillan et al. [16] Own new review
Population Pregnant women and their infants Pregnant women and their newborns Pregnant women and their infants Pregnant women, their fetuses and infants up to 6 months of age Pregnant women and their infants
Intervention Vaccination against influenza Live attenuated or inactivated vaccines Vaccination against influenza Inactivated influenza vaccination Vaccination against seasonal influenza
Comparator Placebo or other vaccines or no vaccination Placebo or no vaccination No vaccination No vaccination Placebo or no vaccination
Outcome Influenza-related outcomes in mother or infant Symptomatic influenza and influenza-like illness; maternal and pregnancy outcomes; neonatal outcomes: congenital malformations, neonatal death Preterm birth, early fetal death, late fetal death Influenza, influenza-like illness, for pregnant women: adverse events and serious adverse events; for the fetus: spontaneous abortion, fetal death, premature birth, low birth weight, small for gestational age, congenital malformation Laboratory-confirmed influenza in mother and/or infant; any severe adverse event in mother or infant