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Table 5 Incremental costs, effectiveness and cost-effectiveness (without ‘provisionally included’ code option)

From: Use of cost-effectiveness analysis to compare the efficiency of study identification methods in systematic reviews

  Safety first Double screening Single screening Single screening with text mining
Resource use and costs—research staff
Resource use item Time (min) Unit cost (£) Cost (£) Time (min) Unit cost (£) Cost (£) Time (min) Unit cost (£) Cost (£) Time (min) Unit cost (£) Cost (£)
 Teleconferences to establish inter-rater reliability 1200 1.175 1410 1200 1.175 1410
 Title-abstract screening 24,954 1.175 29,321 24,954 1.175 29,321 12,477 0.97 12,103 4863 0.97 4717
 Teleconferences to resolve disagreements about title-abstract eligibility (coding) decisions 5400 1.175 6345
 Full-text retrieval 9932 0.97 9634 8752 0.97 8489 9524 0.97 9238 7876 0.97 7640
 Full-text screening 24,830 1.175 29,175 21,880 1.175 25,709 23,810 1.175 27,977 19,690 1.175 23,136
 Teleconferences to resolve disagreements about full-text eligibility (coding) decisions 2950 1.175 3466 2950 1.175 3466 2950 1.175 3466 2950 1.175 3466
Total cost £73,006 £74,740 £52,784 £38,959
Incremental cost £34,047 £35,781 £13,825
Effectiveness—number of inappropriate exclusions avoided
 Recall 100 % 100 % 99 % 95 %
 Number of eligible studies identified 169 169 168 161
Incremental effectiveness 8 8 7
Cost-effectiveness—incremental cost per inappropriate exclusion avoided (ICER)
Base case £4256 £4473 a £1975
 Sensitivity analysis 1a £2718 £2935a £1447
 Sensitivity analysis 1b £5794 £6010a £2502
 Sensitivity analysis 2a £3878 £4187a £1629
 Sensitivity analysis 2b £4633 £4634a £2321
 Sensitivity analysis 3a £4256 £4076b £1975
 Sensitivity analysis 3b £4278 £4892a £2001
 Sensitivity analysis 4a £2128 £2236a £987
 Sensitivity analysis 4b £6384 £6709a £2962
 Sensitivity analysis 5a £4276 £4493a £1998
 Sensitivity analysis 5b £4287 £4504a £2013
  1. All costs are expressed in 20XX GBP (£) prices
  2. aDominated by ‘safety first’
  3. bDominates ‘safety first’
  4. The italics highlight rows containing the principal results