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Table 2 Study description and results for cohort studies

From: Effect of non-surgical, non-pharmacological weight loss interventions in patients who are obese prior to hip and knee arthroplasty surgery: a rapid review

Study, design and quality Demographics Outcomes and results
Inacio et al. [26]   Total THA TKA   THA TKA
 USA No. of participants 9675 2554 7121 DSSI (adjusted OR and 95 % CI) 3.77 (1.59–8.95) 1.67 (0.77–3.61)
 Retrospective cohort Lost ≥5 % of body weight (%)a 1381 (14.3) 444 (17.4) 937 (13.2) SSSI (adjusted OR and 95 % CI) 0.95 (0.27–3.30) 1.41 (0.41–4.85)
 NOS quality score: 9 Gender (% female) who:     90-day Re-ad (adjusted OR and 95 % CI) 1.18 (0.72–1.93) 1.63 (1.16–2.28)
• Lost weight 67 65.1 68.2
• Stayed the same 59.7 52.6 62.1
Age (% <65 years)b 43.9 46.4 43.0    
BMI (%)b       
• ≥30 and <35 kg/m2 52.1 55.2 51.0
• ≥35 kg/m2 39.7 33.3 41.9
Inacio et al. [27]   Total THA TKA   THA TKA
 USA No. of participants 14,784 4066 10,718 DSSI (adjusted OR and 95 % CI) 1.83 (0.83–4.02) 1.27 (0.66–2.42)
 Retrospective cohort Lost ≥5 % of body weight (%)a 2064 (14.0) 732 (18.0) 1332 (12.4) SSSI (adjusted OR and 95 % CI) 1.16 (0.43–3.13) 0.83 (0.29–2.37)
 NOS quality score: 9 Gender (% female) who:     90-day Re-ad (adjusted OR and 95 % CI) 1.05 (0.70–1.57) 1.20 (0.88–1.63)
• Lost weight 64.9 61.2 67
• Stayed the same 60.7 61.2 63.4
• Gained weight 65.3 54.3 68.8
Age (% <65 years)b 46.6 50.8 33.0    
BMI (%)b       
• ≥30 and <35 kg/m2 50.8 53.5 49.7
• ≥35 kg/m2 41.0 35.3 43.2
  1. DSSI deep surgical site infection up to 1 year post-TJA, SSSI superficial surgical site infection within 30 days of TJA, Re-ad readmission, NOS Newcastle Ottawa Scale for cohort studies
  2. aNumber of patients who lost weight pre-operatively and kept it off post-operatively
  3. bPercentage based on total sample size