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Table 1 Structured question

From: Red blood cell transfusion in patients with traumatic brain injury: a systematic review protocol

Population • adult patients with traumatic brain injury
Intervention • red blood cell transfusion
Comparator • no transfusion
Primary outcome • frequency of red blood cell transfusion
Secondary outcomes • transfusion thresholds
• number of red blood cell units transfused
• determinants of red blood cell transfusion
• mortality
• frequency of withdrawal of life-sustaining therapy
• frequency of unfavourable neurological outcome
• ICU and hospital length of stay
• all other reported clinical outcomes
Study design • cohort studies (both prospective and retrospective) and randomized controlled trials