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Table 2 Examples of animal models of acute lung injury

From: Efficacy and safety of mesenchymal stromal cells in preclinical models of acute lung injury: a systematic review protocol

Type of injury Example of model
Infection in lung Intratracheal live bacteria
Bacterial components in lung Intratracheal endotoxin
Systemic infection Cecal ligation and puncture
Systemic bacterial components Systemic endotoxin
Induction by ventilator Ventilator-induced acute lung injury
Chemical or chemotherapeutic Oleic acid
Hydrochloric acid
Shock Hemorrhagic
Trauma Chest trauma
Remote organ injury Ischemia reperfusion