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Protocol for a systematic review and individual participant data meta-analysis of B-type natriuretic peptide-guided therapy for heart failure

  • Maria Pufulete1Email author,
  • Julian PT Higgins2,
  • Chris A Rogers1,
  • Lucy Dreyer1,
  • William Hollingworth2,
  • Mark Dayer3,
  • Angus Nightingale4,
  • Theresa McDonagh5 and
  • Barnaby C Reeves1
Systematic Reviews20143:41

Received: 6 March 2014

Accepted: 7 April 2014

Published: 2 May 2014

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Open Peer Review reports

Pre-publication versions of this article are available by contacting

Original Submission
6 Mar 2014 Submitted Original manuscript
28 Mar 2014 Reviewed Reviewer Report - Mark Rodgers
4 Apr 2014 Author responded Author comments - Maria Pufulete
Resubmission - Version 2
4 Apr 2014 Submitted Manuscript version 2
7 Apr 2014 Editorially accepted
2 May 2014 Article published 10.1186/2046-4053-3-41

How does Open Peer Review work?

Open peer review is a system where authors know who the reviewers are, and the reviewers know who the authors are. If the manuscript is accepted, the named reviewer reports are published alongside the article. Pre-publication versions of the article are available by contacting

You can find further information about the peer review system here.

Authors’ Affiliations

Clinical Trials and Evaluation Unit, University of Bristol, Bristol, UK
School of Social and Community Medicine, University of Bristol, Bristol, UK
Department of Cardiology, Taunton and Somerset NHS Foundation Trust, Taunton, UK
Department of Cardiology, Bristol Heart Institute, Bristol Royal Infirmary, Bristol, UK
Cardiovascular Division, King’s College London, King’s College Hospital, London, UK