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Table 4 Summary effects for the Hpylori dataset after all unpublished studies assigned the same default outlook

From: SAMURAI: Sensitivity analysis of a meta-analysis with unpublished but registered analytical investigations (software)

Scenario number Outlook assigned to all 7 unpublished studies Relative risk (RR) assigned to all unpublished studies Summary effect (RR) Lower 95% confidence limit Upper 95% confidence limit τ2**
1 very positive 0.33 0.518 0.432 0.621 <0.001
2 positive 0.5 0.561 0.471 0.669 <0.001
3 no effect 1 0.697 0.585 0.829 0.011
4 negative 2 0.801 0.609 1.052 0.317
4a* negative 1.5 0.759 0.602 0.958 0.166
5 very negative 3 0.866 0.616 1.217 0.636
5a* very negative 2.5 0.841 0.614 1.151 0.501
6 very positive CL LCL pub,1-α 0.546 0.457 0.652 <0.001
7 positive CL 0.5 RR ^ pub + LC L pub , 1 α 0.573 0.481 0.682 <0.001
8 current effect RR ^ pub 0.591 0.497 0.703 <0.001
9 negative CL 0.5 RR ^ pub + UC L pub , 1 α 0.603 0.507 0.716 <0.001
10 very negative CL UCL pub,1-α 0.634 0.534 0.752 <0.001
  1. (The random number seed used to generate this table was 106.)
  2. *In these cases all unpublished studies were assigned an RR different from the default RR.
  3. **A displayed value of ‘0’ for ‘tau2’ indicates a τ2 value less than 0.001.