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Table 1 Basic characteristics of the included studies

From: The association between sleep disturbances and suicidal behaviors in patients with psychiatric diagnoses: a systematic review and meta-analysis

Author, year

Study design

Patients ( n)

Female (%)

Age (years)

Psychiatric diagnoses

Suicidal behaviors

Sleep disturbances

Agargun, 1997 [7]

Retrospective

113

74%

Mean: 32.6 range: 18-70

Major depression

Ideation

Insomnia and hypersomnia assessed by SCID-I

Li, 2010 [8]

Cross-sectional

1,231

68.20%

Mean: 42.4, range 18-65

Major depression, Bipolar, Other

Attempt

Self-reported insomnia and recurrent nightmares assessed by a questionnaire

McGirr, 2007 [12]

Prospective

156

19.20%

Mean: 42.4

Major depression

Completed suicide

Insomnia and hypersomnia assessed by SCID-I

Nrugham, 2008 [13]

Prospective

2,464

50.80%

Mean age 13.7

Depressive symptom and disorder

Ideation, attempt

Insomnia, hypersomnia, non-restorative sleep assessed by K-SADS and MFQ

Paffenbarger, 1994 [14]

Prospective

21,582

0

Range: 35-74

Depressive disorder

Completed suicide

Self-reported insomnia assessed by a questionnaire

Pompili, 2009 [15]

Retrospective

40

10%

Mean: 40 Range: 23-76

Schizophrenia

Completed suicide

Insomnia defined as difficulty initiating or maintaining sleep, or non-restorative sleep causing impaired functioning or suffering that was long-lasting or demanded treatment and recorded from patients’ medical records

Sjostrom, 2009 [16]

Prospective

165

78%

Range: 18-69

Axis 1 DSM disorders

Attempt

Difficulties initiating sleep, problems maintaining sleep and early morning awakening assessed by USI

Agargun, 1997 [17]

Prospective

41

76%

Mean: 34.6 SD: 10.8

Major depression

SADS suicidality score

Subjective sleep quality, sleep latency, sleep duration, habitual sleep efficiency, sleep disturbance, use of sleeping medications, daytime dysfunction, and global severity measured by PSQI

Agargun, 1998 [18]

Prospective

63

76%

Mean: 34.1 SD: 10.8

Major depression

Ideation, attempts

Frequency of nightmares

Agargun, 1998 [19]

Unclear

67

73.10%

Mean: 31.9 SD: 8.8

Panic disorder

Ideation

Sleep panic and insomnia ascertained from SADS

Agargun, 2003 [20]

Prospective

26

61.50%

Unclear

Major depression

HDRS suicide scores

REM latency, REM%, REM periods measured by three nights of polysomnography

Chellappa, 2007 [21]

Cross-sectional

70

62.90%

Mean:: 40.5 SD: 12.54

Major depression

Ideation

Insomnia or excessive sleepiness assessed by the SHQ and ICSD

Krakow, 2000 [22]

Prospective

153

100%

Mean: 36.4 SD: 11.1

PTSD

Hamilton Depression and suicidality scores

SMD and SDB assessed by AASM 1997 and ASDA 1997

Agargun, 2007 [23]

Retrospective

100

52%

Mean: 32.1 SD: 10.7

Unipolar major depression

Attempt

Nightmares assessed by ICSD-R; insomnia assessed by the HDRS items 6, 7, and 8

Yoshimasu, 2006 [24]

Cross-sectional

231

57.10%

Mean: 36.3 SD: 28.5

Major depression

Ideation

Insomnia assessed by SDS, KMI, and patients’ three most painful complaints

Bjorngaard 2011 [25]

Prospective

74,977

51%

Mean: 37.9 SD: 16.0

Anxiety, depression

Completed suicide

Self-reported sleep difficulties assessed by a questionnaire

Li 2012 [26]

Prospective

419

81.80%

Mean: 44.6 SD: 10.4

Major depression

Ideation

Insomnia, nightmares, and frequency of sleep disturbances measured by a questionnaire

Krakow 2011 [27]

Cross-sectional

1,584

55%

Mean: 49.8 SD: 66.4

Depression

Attempt

Sleep disturbances measured by SMH, ISI DDNSI, FOSQ, and TMB-10

Fawcett, 1990 [1]

Prospective

954

58%

Mean: 38.1 Range: 17-79

Major affective disorder

Completed suicide

Insomnia assessed by SADS

  1. AASM: American Academy of Sleep Medicine; ASDA: American Sleep Disorders Association; DDNSI: Disturbing Dream and Nightmare Severity Index; FOSQ: Functional Outcomes Sleep Questionnaire; HDRS: Hamilton Depression Rating Scale; ICSD: International Classification of Sleep Disorders diagnostic criteria for sleep disorders due to mood disorders; ICSD-R: International Classification of Sleep Disorders, revised; ISI: Insomnia Severity Index; KMI: Kyudai Medical Inventory; K-SADS: Kiddie-Schedule for Affective Disorders and Schizophrenia; MFQ: Mood and Feelings Questionnaire; PSQI: Pittsburgh Sleep Quality Index; PTSD: Post-traumatic stress disorder; REM: Rapid eye movement; SADS: Schedule for Affective Disorders and Schizophrenia; SCID-I: Structured Clinical Interview for DSM-IV-TR Axis I Disorders; SD: standard deviation; SDB: Sleep-disordered Breathing; SDS: Self-rating Depression Scale; SHQ: Sleep Habits questionnaire; SMD: Sleep-related Movement Disorders; SMH: Sleep Medicine History; TMB-10: Time Monitoring Behavior; USI: Uppsala Sleep Inventory.