Skip to main content

Table 3 Comparison of existing evidence on effectiveness of weight management interventions and the proposed IPD meta-analysis

From: Study protocol: differential effects of diet and physical activity based interventions in pregnancy on maternal and fetal outcomes—individual patient data (IPD) meta-analysis and health economic evaluation

Characteristics Existing systematic reviews Published and ongoing primary studies Proposed IPD meta-analysis
Consistent inclusion and exclusion criteria e.g. BMI, risk status x
Assessment of effect of prognostic factors on treatment effect e.g. diabetic status, chronic hypertension x
Missing data observed and accounted at individual level x
All critically important maternal and fetal outcomes considered x
Potential for sufficient power to assess for differential treatment effect across groups e.g. BMI, ethnicity, race, parity x x
Standardisation of statistical analysis across studies x N/A
Correlation between multiple end points accounted e.g. each participant providing data on gestational weight gain in various trimesters and weight retention postpartum x
Up to date follow-up information, potentially longer than that used in the original study publication x x