Consistent inclusion and exclusion criteria e.g. BMI, risk status
|
x
|
√
|
√
|
Assessment of effect of prognostic factors on treatment effect e.g. diabetic status, chronic hypertension
|
x
|
√
|
√
|
Missing data observed and accounted at individual level
|
x
|
√
|
√
|
All critically important maternal and fetal outcomes considered
|
√
|
x
|
√
|
Potential for sufficient power to assess for differential treatment effect across groups e.g. BMI, ethnicity, race, parity
|
x
|
x
|
√
|
Standardisation of statistical analysis across studies
|
x
|
N/A
|
√
|
Correlation between multiple end points accounted e.g. each participant providing data on gestational weight gain in various trimesters and weight retention postpartum
|
x
|
√
|
√
|
Up to date follow-up information, potentially longer than that used in the original study publication
|
x
|
x
|
√
|