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Table 2 Comparative effectiveness reviews assessed a

From: Assessment of a method to detect signals for updating systematic reviews

CER 2009 prediction Update commissioned by AHRQ
Comparative Effectiveness of Management Strategies for Gastroesophageal Reflux Disease[11] High Yes
Effectiveness of Noninvasive Diagnostic Tests for Breast Abnormalities[12] High Yes
Comparative Effectiveness of Epoetin and Darbepoetin for Managing Anemia in Patients Undergoing Cancer Treatment[13] High Yes
Comparative Effectiveness and Safety of Analgesics for Osteoarthritis[14] High Yes
Efficacy and Comparative Effectiveness of Off-Label Use of Atypical Antipsychotics[15] Medium Yes
Comparative Effectiveness of Drug Therapy for Rheumatoid Arthritis and Psoriatic Arthritis in Adults[16] Medium Yes
Comparative Effectiveness of Treatments to Prevent Fractures in Men and Women with Low Bone Density or Osteoporosis[17] Medium Yes
Comparative Effectiveness of Second-Generation Antidepressants in the Pharmacologic Treatment of Adult Depression[18] Low Yes
Comparative Effectiveness of Angiotensin-Converting Enzyme Inhibitors (ACEIs) and Angiotensin II Receptor Antagonists (ARBs) for Treating Essential Hypertension[19] Low Yes
Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer b[20] Medium No
Comparative Effectiveness of Percutaneous Coronary Interventions and Coronary Artery Bypass Grafting for Coronary Artery Disease c[21] Low No
  1. aAHRQ, Agency for Healthcare Research and Quality; CER, comparative effectiveness review. bUpdate not commissioned pending publication of the PIVOT trial. cUpdate not commissioned or individual patient data meta-analysis had already been commissioned.