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Table 2 Summary of a systematic review of prognostic studies in the field of recurrent pain in children and adolescents

From: Judging the quality of evidence in reviews of prognostic factor research: adapting the GRADE framework

Recent systematic review Description
Huguet A, et al., in preparation We have conducted a systematic review of the literature examining risk and protective factors for the onset and course of several chronic pain conditions in children and adolescents. The scope of this review is very broad because we have considered multiple etiological and prognostic factors combined with multiple outcomes.
Through a search of PubMed, EMBASE, PsycInfo, CINAHL, and Web of Science from inception until February 2013, we included all manuscripts that meet the following criteria: studies were included if they were a cohort prospective or retrospective study with at least 3 months of follow-up quantitatively investigating through inferential statistics the prediction of the onset, persistence of chronic or recurrent pain conditions and pain-related disability from childhood or adolescence. Studies were excluded if they were non-English or the population had cognitive impairments or life threatening illnesses.
  Throughout this article we will provide examples of evidence of potential risk and protective factors associated with the course of headaches in children and adolescents in an attempt to provide a practical overview of the application of the GRADE for prognostic evidence.