Table 2 Input data from individual randomized trials

Baseline

At least available input data:

Trial number

Created by OA Trial Bank

Patient ID

Random number

Date of randomization

Date

Age

Continuous

Gender

Dichotomous (male/female)

Body mass index (or weight and length)

Continuous

Type of osteoarthritis

Dichotomous (hip/knee)

Type of intervention

String variable

Pain severity (VAS, NRS, WOMAC, other)

Continuous

Collected for current pilot study:

Signs of inflammation

Depends on measurement method

- physical examination

- imaging (that is, sonography, magnetic resonance imaging)

- additional testing (ESR, CRP, inflammatory markers)

Collected when available:

Osteoarthritis characteristics:

Depends on measurement method

- American College of Rheumatology criteria

- Severity

- Radiographic information

- Kellgren and Lawrence score

Duration of complaints

Continuous or dichotomous

Physical functioning (WOMAC/KOOS/KSS/…)

Continuous

Patient global assessment

Continuous or dichotomous

Outcome measures at follow-up

At least available input data:

Pain severity (VAS, NRS, WOMAC, other)

Continuous

Collected when available:

Physical functioning (WOMAC/KOOS/KSS/…)

Continuous

Patient global assessment

Continuous or dichotomous