| Galactomannan review | MRI versus CT review | Physical examination review |
---|---|---|---|
Index test(s) | Galactomannan sandwich ELISA (Platelia©) | Diffusion-weighted MRI and CT (for the diagnosis of acute ischemic stroke); MRI (for the diagnosis of acute hemorrhagic stroke) | A number of physical examination tests such as straight leg raising and crossed straight leg raising tests. |
Reference standard | EORTC/MSG criteria (see review) | Acute ischemic stroke: a combination of clinical and imaging information supported by clinical or imaging follow-up (CT or MRI) or autopsy; | Diagnostic imaging or findings at surgery |
Acute hemorrhagic stroke: a clinical diagnosis supported by CT or autopsy | |||
Target condition | Invasive aspergillosis | Acute ischemic stroke; acute hemorrhagic stroke | Radiculopathy due to lower lumbar disc herniation |
Presentation of the results from meta-analysis | Estimates of sensitivity and specificity (percentages) and false positive and false negative rates (natural frequencies) | Estimates of sensitivity and specificity (percentages) | Estimates of sensitivity and specificity (percentages) |