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Table 2 Characteristics of reviewed studies, ordered by base year of cost data

From: Economic analyses of breast cancer control in low- and middle-income countries: a systematic review

Authors

Region / country

Base year of cost data

Study population

Breast cancer stage considered

Economic evaluation type

Study design

Perspective

Time horizon

Effectiveness outcome measure

Sources for estimation of effectiveness

Sources for estimation of resource utilization

Discount rates used

Sensitivity analysis for assumptions presented

Incremental analysis reported

Groot and colleagues, 2006 [28]

World sub-regions

2000

Female population at risk, in AfrE, AmroA, SearD

All

Cost-effectiveness analysis

Model based

Healthcare

100 years

DALYs

Literature based

Secondary data collection

On both costs and effects

Yes

Yes

Okonkwo and colleagues, 2008 [30]

India

2001

Female population at risk

All

Cost-effectiveness analysis

Model based

Healthcare

25 years

Life years saved

Secondary data collection

Secondary data collection

On both costs and effects

Yes

Yes

Munshi, 2009 [41]

Worldwide

Varying from 2002 to 2007

Breast cancer patients in general

All

Report on costs and effects separately

Other

Healthcare

NA

Intermediate outcome measures

Literature based

Literature

NA

NA

NA

Sarvazyan and colleagues, 2008 [32]

Worldwide

Varying from 2003 to 2007

Female population at risk

All

Cost-effectiveness analysis

Other

Not stated

1 year

Life years saved

Literature based

Literature

NA

Yes

No

Fonseca and colleagues, 2009 [38]

Brazil

2005

Hypothetical cohort of 64-year-old postmenopausal women

All

Cost-effectiveness analysis

Model based

Healthcare

Lifetime

Life years saved

Literature based

Expert opinion

On both costs and effects

Yes

Yes

Ginsberg and colleagues, 2012 [27]

Sub-Saharan Africa and South East Asia

2005

Female population at risk, in SearD and AfrE

All

Cost-effectiveness analysis

Model based

Healthcare

100 years

DALYs

Literature based

Secondary data collection

On both costs and effects

Yes

Yes

Salomon and colleagues, 2012 [31]

Mexico

2005

Female population at risk

All

Cost-effectiveness analysis

Model based

Healthcare

100 years

DALYs

Literature based

Secondary data collection

On both costs and effects

Yes

Yes

Pakseresht and colleagues, 2011 [48]

India

2006/2007

103 women with primary breast cancer in a tertiary hospital

All

Cost analysis/cost of illness

Observational

Non-healthcare

2 years

NA

NA

Primary data collection

NA

NA

NA

Yazihan and Yilmaz, 2006 [34]

Turkey

2007

Female population at risk

All

Cost-effectiveness analysis

Other

Healthcare

6 years

DALYs

Secondary data collection

Secondary data collection

None

No

No

Bastani and Kiadaliri, 2012 [49]

Iran

2008

Patients younger than 75 with node-positive breast cancer

All

Cost-utility analysis

Experimental

Healthcare

8 months

QALYs

Primary data collection

Primary data collection

NA

No

NA

Liubao and colleagues, 2009 [39]

China

2008

Model cohort of 1,000 51-year-old operable breast cancer patients

All

Cost-effectiveness analysis

Model based

Healthcare

Lifetime

QALYs

Secondary data collection

Secondary data collection

On both costs and effects

Yes

Yes

Astim, 2011 [36]

Turkey

2010

Female population at risk older than 30

All

Report on costs and effects separately

Model based

Healthcare

10 years

Intermediate outcome measures

Secondary data collection

Literature

Yes

No

No

Zelle and colleagues, 2012 [35]

Ghana

2010

Female population at risk

All

Cost-effectiveness analysis

Model based

Healthcare

100 years

DALYs

Literature based

Primary data collection

On both costs and effects

Yes

Yes

Bai and colleagues, 2012 [42]

China

2012

Model cohort of women aged 51.7, with early stage breast cancer after lumpectomy

1 and 2

Cost-effectiveness analysis

Model based

Healthcare

Lifetime

QALYs

Literature based

Literature/expert opinion

On both costs and effects

Yes

Yes

Arredondo and colleagues, 1995 [43]

Brazil

Not clear

Hypothetical breast cancer case

All

Cost analysis/cost of illness

Observational

Healthcare

NA

NA

NA

Expert opinion

NA

No

No

Boutayeb and colleagues, 2010 [37]

Morocco

Not clear

Early-stage breast cancer patients in Morocco

Not clear

Cost-effectiveness analysis

Observational

Healthcare

1 year

Life years saved

Literature based

Secondary data collection

NA

No

No

Denewer and colleagues, 2010 [26]

Egypt

Not clear

Female population at risk between 25 and 65 years

All

Report on costs and effects separately

Experimental

Healthcare

2 years

Intermediate outcome measures

Primary data collection

Not clear

None

No

No

Guggisberg and colleagues, 2011 [46]

Cameroon

Not clear

Women who underwent FNA in a rural hospital

All

Report on costs and effects separately

Observational

Healthcare

5 weeks

Intermediate outcome measures

Primary data collection

Not clear

NA

No

No

Kobayashi, 1988 [44]

Worldwide

Not clear

NA

NA

Cost analysis/cost of illness

Observational

Healthcare

NA

Intermediate outcome measures

Primary data collection

Primary data collection

NA

NA

NA

Love and colleagues, 2002 [40]

Vietnam and China

Not clear

Premenopausal Vietnamese and Chinese breast cancer patients, considered for surgery

2

Cost-effectiveness analysis

Experimental

Healthcare

15 years

Life years saved

Primary data collection

Not clear

On both costs and effects

No

Yes

Mousavi and colleagues, 2008 [29]

Iran

Not clear

Female population at risk between 35 and 69

All

Report on costs and effects separately

Other

Healthcare

1 year

Life years saved

Expert opinion

Expert opinion

NA

No

No

Nasrinossadat and colleagues, 2011 [47]

Iran

Not clear

51 patients that underwent surgical excision of nonpalpable breast masses

All

Report on costs and effects separately

Observational

Healthcare

3 to 4 years

Intermediate outcome measures

Primary data collection

Not clear

None

No

No

Thomas and colleagues, 1999 [45]

Nigeria

Not clear

Patients who received FNA between 1994 and 1997

All

Report on costs and effects separately

Observational

Patient

NA

Intermediate outcome measures

Primary data collection

Not clear

NA

NA

NA

  1. DALYs, disability-adjusted life years; FNA, fine needle aspiration; NA, not applicable; QALYs, quality-adjusted life years.