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Table 2 Characteristics of 24 comparative effectiveness reviews (CERs) and their associated updating surveillance assessments

From: A surveillance system to assess the need for updating systematic reviews

CER title; first author last name (publication date) Latest search date for CER (across databases) Number of included studies in CER (total or per KQ) Period covered by surveillance assessment search Number of new studies judged as relevant for inclusion in CER
(Journal publication, if available) Time between search and report release   Time between original searches and update search  
Comparative Effectiveness of Therapies for Clinically Localized Prostate Cancer; Wilt (February 2008) [22] September 2007 436 January 2007 to March 2012 21
(Systematic review: association Between Hospital and Surgeon Radical Prostatectomy Volume and Patient Outcomes: A Systematic Review) [35] 5 months   54 months  
Comparative Effectiveness of Medications to Reduce Risk of Primary Breast Cancer in Women; Nelson (September 2009) [11] January 2009 13 (KQ1,KQ3) January 2008 to July 2011 3
(Systematic review: comparative effectiveness of medications to reduce risk for primary breast cancer) [36] 8 months 70 (KQ2,KQ3) 31 months  
   24 (KQ4)   
   16 (KQ5)   
Comparative Effectiveness of Core Needle Biopsy and Open Surgical Biopsy for Diagnosis of Breast Lesions; Bruening (December 2009) [10] September 2009 107 (KQ1-2) January 2008 to September 2011 19
(Systematic review: comparative effectiveness of core-needle and open surgical biopsy to diagnose breast lesions) [37] 3 months NA (KQ3) 24 months  
Effectiveness of Recombinant Human Growth Hormone (rhGH) in the Treatment of Patients with Cystic Fibrosis; Phung (October 2010) [12] April 2010 26(KQ1-2, KQ4, KQ6-7); 50 (KQ3); 3(KQ5) January 2010 to August 2011 16
(Systematic review: recombinant human growth hormone in the treatment of patients with cystic fibrosis) [38] 6 months   16 months  
Therapies for Children with Autism Spectrum Disorders; Warren (April 2011) [13] May 2010 159 January 2009 to October 2011 15
(Systematic review: a systematic review of early intensive intervention for autism spectrum disorders) [39] 11 months   17 months  
Comparative Effectiveness of Traumatic Brain Injury and Depression; June 2010 115 January 2010 to October 2011 29
Guillamondegui (April 2011) [15] 10 months   16 months  
Pain Management Interventions for Hip Fracture; Abou-Setta (May 2011) [14] December 2010 98 January 2008 to November 2011 1
(Systematic review: comparative effectiveness of pain management interventions for hip fracture: a systematic review) [40] 5 months   11 months  
Diagnosis and Treatment of Obstructive Sleep Apnea in Adults; Balk (August 2011) [27] September 2010 44 (KQ1); 1 (KQ2); 2 (KQ3); 11 (KQ4); 173 (KQ5); 6 (KQ6); 18 (KQ7) January 2010 to April 2012 35
(Systematic review: auto-titrating versus fixed continuous positive airway pressure for the treatment of obstructive sleep apnea: a systematic review with meta-analyses) [41] 11 months   19 months  
Nonpharmacologic Interventions for Treatment-Resistant Depression in Adults; Gaynes (September 2011) [30] 18 November 2010 64 January 2010 to March 2012 9
  10 months   16 months  
Attention Deficit Hyperactivity Disorder (ADHD): Effectiveness of Treatment in At-Risk Preschoolers; Long-term Effectiveness in All Ages; and Variability in Prevalence, Diagnosis, and Treatment; Charach (October 2011) [33] 31 May 2010 53 (KQ1); 76 (KQ2); NR (KQ3) January 2010 to June 2012 17
  17 months   25 months  
Effectiveness of Early Diagnosis, Prevention, and Treatment of Clostridium difficile Infection; Butler (December 2011) [29] June 2010 and for KQ3 May 2011 13 (KQ1); 36 (KQ2); 13 (KQ3); 40 (KQ4) January 2010 to June 2012 7
(Systematic review: comparative effectiveness of Clostridium difficile treatments: a systematic review) [42] 7 to 18 months   24 months for KQ 1,2, 4  
    13 months for KQ3  
Noncyclic Chronic Pelvic Pain Therapies for Women: Comparative Effectiveness; Andrews (January 2012) [28] May 2011 23 (KQ1); 7 (KQ2); 0 (KQ3); 17 (KQ4); 0 (KQ5) May 2011 to July 2012 2
(Systematic review: systematic review of therapies for noncyclic chronic pelvic pain in women) [43] 8 months   14 months  
Chronic Kidney Disease Stages 1 to 3: Screening, Monitoring, and Treatment; January 2011 110 January 2011 to August 2012 20
Fink (January 2012) [31] 12 months   19 months  
(Systematic review: screening for, monitoring, and treatment of chronic kidney disease stages 1 to 3: a systematic review for the US Preventive Services Task Force and for an American College of Physicians Clinical Practice Guideline) [44]     
First and second generation antipsychotics for children and young adults; Seida (February 2012) [32] February 2011 81 January 2011 to August 2012 19
(Systematic review: antipsychotics for children and young adults: a comparative effectiveness review) [45] 12 months   18 months  
Comparative Effectiveness of Management Strategies for Renal Artery Stenosis: 2007 Update; Balk (November 2007) [26] 23 April 2007 8 October 2006 to June 2012 7
  7 months   62 months  
Comparative Effectiveness of Radiofrequency Catheter Ablation for Atrial Fibrillation; IP (July 2009) [18] December 2008 120 June 2008 to September 2011 33
(Systematic review: comparative effectiveness of radiofrequency catheter ablation for atrial fibrillation) [46] 7 months   35 months  
Comparative Effectiveness of Lipid-Modifying Agents; Sharma (September 2009) [17] May 2009 101 November 2008 to October 2011 20
(Systematic review: comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemia) [47] 4 months   29 months  
Comparative Effectiveness of Angiotensin Converting Enzyme Inhibitors or Angiotensin II Receptor Blockers Added to Standard Medical Therapy for Treating Stable Ischemic Heart Disease; Coleman (October 2009) [20] February 2009 60 August 2008 to November 2011 12
(Systematic review: comparative effectiveness of angiotensin-converting enzyme inhibitors or angiotensin II-receptor blockers for ischemic heart disease) [48] 8 months   33 months  
Comparative Effectiveness of In-Hospital Use of Recombinant Factor VIIa for Off-Label Indications versus Usual Care; Yank (May 2010) [16] August 2009 74 February 2009 to January 2012 15
(Systematic review: benefits and harms of in-hospital use of recombinant factor VIIa for off-label indications) [49] 9 months   29 months  
Comparative effectiveness and safety of radiotherapy treatments for head and neck cancer; Samson (May 2010) [19] September 2009 108 March 2009 to August 2011 7
  8 months   23 months 15
Comparative Effectiveness of Nonoperative and Operative Treatments for Rotator Cuff Tears; Sedia (July 2010) [21] September 2009 137 March 2009 to January 2012  
(Systematic review: nonoperative and operative treatments for rotator cuff tears) [50] 10 months   28 months  
Comparative Effectiveness of Terbutaline Pump for the Prevention of Preterm Birth; Gaudet (September 2011) [23] April, 2011 14 October 2010 to March 2012 0
(Systematic review: effectiveness of Terbutaline Pump for the Prevention of Preterm Birth. A Systematic Review and Meta-Analysis) [51] 5 months   11 months  
Self-Measured Blood Pressure Monitoring: Comparative Effectiveness; Uhlig (January 2012) [24] 19 July 2011 48 (KQ1-2); 1( KQ5) January 2011 to August 2012 1
  6 months 0 (KQ 3–4) 13 months  
Hematopoietic Stem-Cell Transplantation in the Pediatric Population; Ratko (February 2012) [25] 17 August 2011 251 February 2011 to September 2012 0
  6 months   13 months  
  1. Abbreviations: CER Comparative Effectiveness Review, KQ key question, NR not reported.
  2. Legend: Columns 1 to 3 present characteristics of CERs:
  3. Column 1: title of the CER, first author’s last name, and title of the journal publication for the same CER.
  4. Column 2: the date that last search was executed for the original CER (for instance, 17 August 2011 refers to the last literature search date carried out for CER), and the time lag between the last search date and the release date of the original CER on the AHRQ website; for example, six months shows the CER was published/released on the AHRQ website six months after the last search date was executed for the CER.
  5. Column 3: total number of studies included in the original CER; for example 251 means a total of 251 studied had met the inclusion criteria of the original CER and were reported in the original CER.
  6. Column 4 presents: 1) time period that the surveillance assessment search has covered (for instance, February 2011 to September 2012 means the search was limited to the period between these dates), and 2) time lag between the original CER search date and the surveillance assessment search date (for example, 13 months means the surveillance literature search was carried out 13 months after the last search date of the original CER).
  7. Column 5 reports the number of studies include in the surveillance assessment; for instance, (15) shows that a total of 15 studies deem eligible and were reported in the surveillance assessment.