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Table 2 Characteristics of studies included in the review

From: Survival of patients with non-small cell lung cancer without treatment: a systematic review and meta-analysis

Study N Study period (years) Disease Stage Histology Male Median Age (years)
I II squamous adeno large-cell
(a) Cohort studies
Raz 2007 1432 13 1432 NR 460 419 89 747 74
Wisnivesky 2007a 2344 8 NR NR NR NR NR 1292 NR
Chadha 2005 39 11 23 13 18 88 5 4 77
Henschke 2003 131 7 131 NR NR NR NR NR NR
McGarry 2002a 49 5 NR NR NR NR NR 49 NR
Vrdoljak 1994 130 7 55 56 61 35 34 120 60
Hyde 1973 293 8 NR NR NR NR NR NR NR
Total/(Range) 4418 (5 to 13) 1641 68 539 542 128 2211  
(b) RCTs    III IV      
Goss 2009c 101 2 (0.23) 17 84 25 46 11 61 76
Anderson 2000 150 2 92 58 NR NR NR 91 64
ELVIS 1999c 78 1 (1.08) 22 56 33 29 3 69 74b
Cullen 1999c 176 8 (2.17) 88 88 103 42 6 122 64
Thongprasert 1999 98 4 49 49 31 49 12 NR 60
Helsing 1998c 26 5 (3.33) 3 23 5 17 4 18 65
Cartei 1993 50 7 NR 50 25 17 8 36 57
Leung 1992c 66 4 (3.58) 58 NR 31 18 7 48 62
Cellerino 1991 61 3 61 NR 38 18 5 59 62
Quoix 1991 22 3 NR 22 NR NR NR NR NR
Kaasa 1991 43 3 NR 43 16 16 11 31 62b
Ganz 1989 26 2 NR 26 9 17 NR 23 NR
Rapp 1988 50 3 50 NR 12 24 12 38 58
Cormier 1982 17 2 17 NR 8 2 6 16 60
Laing 1975 67 2 15 20 23 5 9 59 64
Total/(Range) 1031 (1 to 8) 472 519 359 300 94 671 (57 to 76)
  1. N = Sample size or number of participants enrolled; NR = data not reported; adeno, = adenocarcinoma; squamous, = squamous cell carcinoma; large-cell, = large-cell carcinoma; asample includes stage I and II cancer; brecorded mean age where median age was not reported or not extractable, cmedian follow-up in parenthesis.