|
Enrolling years
|
2000 to 2002
|
1995 to 1998
|
1995 to 1997
|
1991 to 2001
|
1996 to 1998
|
|
Randomized
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
|
- Blinded?
|
Yes
|
Yes
|
N/A
|
N/A
|
Yes
|
|
- When?
|
Pre-intervention
|
Pre-intervention
|
Post-intervention
|
Pre-intervention
|
Pre-intervention
|
|
Intention-to-treat analysis
|
No
|
Yes
|
No
|
Yes
|
Yes
|
|
Exclusion criteria
|
|
- Long lesions
|
Yes (> 25 mm)
|
No
|
Yes (> 15 mm)
|
No
|
Yes (> 25 mm)
|
|
- Bifurcation
|
Yes
|
No
|
No
|
Yes
|
Yes
|
|
- Left main coronary artery
|
Yes
|
Yes
|
No
|
No
|
Yes
|
|
- Chronic total occlusion
|
Yes
|
Yes
|
Yes
|
Yes
|
No
|
|
- Recent acute coronary syndrome
|
Yes
|
No (except MI with TIMI flow grade < 3)
|
Yes
|
Yes
|
Yes
|
|
- Small vessels
|
Yes (≤ 2.75 mm)
|
Yes (< 2.5 mm)
|
Yes (< 3 mm)
|
Yes (< 3 mm)
|
Yes (< 2.5 mm)
|
|
- Others
|
Age < 18 and > 70 y; extensive calcification; saphenous vein graft lesions
|
Age < 18 y; non-covered dissection; large vessels (> 3.25 mm)
|
Previous CABG
|
Focal (< 20 mm) or ostial lesions
| |
|
Pre-intervention IVUS
|
Yes
|
No
|
No
|
Yes
|
Yes
|
|
Post-intervention IVUS
|
Yes
|
Yes
|
Yes
|
Yes
|
Yes
|
|
PCI success criteria
|
Stent CSA/average CSA > 80%, complete apposition, stent CSA > 7.5 mm2
|
Stent CSA/distal CSA > 90%, complete apposition, no dissection
|
Stent CSA/average CSA > 80%
|
Stent MLD/average MLD > 80%, complete apposition, stent CSA ≥ distal CSA
|
Stenosis < 10% and MUSIC study criteria [10]
|
|
- PCI success by IVUS,%
|
96
|
63
|
61
|
89
|
82.2 and 56 (MUSIC)
|
|
Clinical follow-up, months
|
6
|
12
|
18
|
12
|
12
|
|
Angiographic follow-up, months
|
6*
| |
6 (com USIC)
|
6
|
6
|
|
MACE
|
Death, nonfatal MI, repeat revascularization†
|
Without explicit criteria
|
Death, repeat revascularization†
|
Death, nonfatal MI, clinical TLR
|
Death, nonfatal MI, repeat revascularization†
|
