Table 2 Study characteristics

Enrolling years

2000 to 2002

1995 to 1998

1995 to 1997

1991 to 2001

1996 to 1998

Randomized

Yes

Yes

Yes

Yes

Yes

- Blinded?

Yes

Yes

N/A

N/A

Yes

- When?

Pre-intervention

Pre-intervention

Post-intervention

Pre-intervention

Pre-intervention

Intention-to-treat analysis

No

Yes

No

Yes

Yes

Exclusion criteria

- Long lesions

Yes (> 25 mm)

No

Yes (> 15 mm)

No

Yes (> 25 mm)

- Bifurcation

Yes

No

No

Yes

Yes

- Left main coronary artery

Yes

Yes

No

No

Yes

- Chronic total occlusion

Yes

Yes

Yes

Yes

No

- Recent acute coronary syndrome

Yes

No (except MI with TIMI flow grade < 3)

Yes

Yes

Yes

- Small vessels

Yes (≤ 2.75 mm)

Yes (< 2.5 mm)

Yes (< 3 mm)

Yes (< 3 mm)

Yes (< 2.5 mm)

- Others

Age < 18 and > 70 y; extensive calcification; saphenous vein graft lesions

Age < 18 y; non-covered dissection; large vessels (> 3.25 mm)

Previous CABG

Focal (< 20 mm) or ostial lesions

Pre-intervention IVUS

Yes

No

No

Yes

Yes

Post-intervention IVUS

Yes

Yes

Yes

Yes

Yes

PCI success criteria

Stent CSA/average CSA > 80%, complete apposition, stent CSA > 7.5 mm²

Stent CSA/distal CSA > 90%, complete apposition, no dissection

Stent CSA/average CSA > 80%

Stent MLD/average MLD > 80%, complete apposition, stent CSA ≥ distal CSA

Stenosis < 10% and MUSIC study criteria [10]

- PCI success by IVUS,%

96

63

61

89

82.2 and 56 (MUSIC)

Clinical follow-up, months

6

12

18

12

12

Angiographic follow-up, months

6^*

6 (com USIC)

6

6

MACE

Death, nonfatal MI, repeat revascularization^†

Without explicit criteria

Death, repeat revascularization^†

Death, nonfatal MI, clinical TLR

Death, nonfatal MI, repeat revascularization^†