Table 2 Review outcomes
From: A protocol for a systematic review for perioperative pregabalin use
| Type of outcome | Outcome |
|---|---|
| Primary perioperative efficacy outcomes | · Pain relief at rest and on movement (any measure) |
| · Reduction in postoperative opioid and other analgesic consumption (dose, frequency, and time of first use of rescue analgesia) | |
| Secondary perioperative and long-term outcomes | · Postoperative nausea and vomiting |
| · Anxiolysis | |
| · Sleep restoration | |
| · Early ambulation | |
| · Early feeding | |
| · Length of hospital stay | |
| · Chronic postoperative pain | |
| Perioperative harms outcomes | · Somnolence |
| · Sedation | |
| · Visual disturbances | |
| · Confusion | |
| · Respiratory depression | |
| · Cognitive dysfunction | |
| · Withdrawal due to adverse events | |
| · Participants with at least one serious adverse event (as defined by the FDA) | |
| · Mortality | |
| · Participants with at least one adverse event | |
| · Withdrawal due to lack of pregabalin efficacy | |
| FDA: Food and Drugs Administration | |
