Table 1 Randomized controlled trials of APAP versus CPAP: baseline study characteristics
Study PMID | Study design | Mean age (years) | Male, % | Mean body mass index (kg/m2) | Baseline AHI (SD) | Previous CPAP? | Funding | Quality issues |
|---|---|---|---|---|---|---|---|---|
d'Ortho 2000 [32] 11035671 | XO | 57 | 88 | 32 | 58 (6) | No | Industry/Non-industry combined | - |
Damjanovic 2009 [10] 19129293 | PL | 57 | 78 | 31.1 | 44 (25) | No (new Dx) | nd | - |
Fietze 2007 [11] 17337881 | PL | 54 | 95 | 30.9 | 42 (26) | No (new Dx) | Industry | Incomplete reporting; patient selection unclear |
Galetke 2008 [12] 17148931 | XO | 56 | 80 | 29.3 | 33 (19) | No (new Dx) | nd | Incomplete reporting; small sample and no power calculation |
Hudgel 2000 [18] 10947032 | XO | 46 | 54 | 42 | 30 (25) | No | nd | Incomplete reporting; 35% dropout |
Hukins 2004 [19] 15683142 | XO | 50 | 87 | 35.2 | 50 (25) | No | Industry | - |
Hussain 2004 [20] 15072173 | XO | 45 | 90 | 35.9 | 47 (36) | No | Industry | Patient recruitment method unclear; small sample and no power calculation |
Konermann 1998 [31] 9515848 | PL | 54 | 88 | 32.1 | 38 (14) | nd | nd | - |
Marrone 2004 [21] 15165530 | XO | 53 | 95 | 32.9 | 68 (12) | No | nd | Small sample and no power calculation |
Massie 2003 [22] 12406840 | XO | 49 | 82 | 32 | nd | No (new Dx, implied) | Industry | Incomplete reporting |
Meurice 2007 [13] 17638595 | PL | 55 | nd | 30.8 | 55 (10) | No (no Tx) | nd | Patient recruitment unclear |
Nolan 2007 [14] 17326544 | XO | 53 | 90 | 29.9 | 15 (8) | No (new Dx) | Non-industry | - |
Noseda 2004 [23] 15249439 | XO | 49 | 96 | 32.3 | nd | No | nd | - |
Nussbaumer 2006 [15] 16537862 | XO | 49 | 90 | 31.1 | 41 (20) | nd | Industry | - |
Patruno 2007 [16] 17494789 | PL | 48 | 81 | 36.5 | 46 (14) | No (new Dx) | Non-industry | Incomplete reporting |
Planes 2003 [29] 12683473 | PL | 54 | 77 | 32.4 | 59 (17) | No (new Dx) | Industry (unclear) | Patient recruitment unclear |
Randerath 2001 [26] 11254519 | XO | 55 | 87 | 32.4 | 35 (26) | nd | Industry | - |
Resta 2004 [24] 15679008 | PL | 33 | 90 | 36.7 | 47 (11) | No (no Tx) | nd | Incomplete reporting |
Senn 2003 [25] 14525804 | XO | 53 | 79 | 33.3 | 46 (23) | No | nd | - |
Sériès 1997 [27] 9341056 | PL | 36-65 (range) | nd | 36.4 | 44 (20) | No (no Tx) | Industry | Potential selection bias |
Teschler 2000 [28] 10885414 | XO | 52 | 100 | 33.8 | 53 (26) | No (new Dx) | nd | Incomplete reporting; small sample |
To 2008 [17] 18197915 | XO | 46 | nd | 28.7 | 54 (nd) | No (new Dx) | nd | - |
Vennelle 2010 [30] 20175411 | XO | 50 | 77 | 34.5 | 33 (18) | No (new Dx) | nd | - |
West 2006 [33] 16254055 | PL | 46.5a | 85 | nd | nd | No | Industry | - |